Parkinson’s disease (PD) is a whole body disease clinically defined by the degeneration of nerves in the brain, leading to symptoms like stiff muscles, difficulty with bodily movements, tremors, sleep issues, difficulty speaking, anxiety or apathy and much more. Other than the genetic factors, the role and the contribution of various environmental and lifestyle factors have gained importance recently. Importantly, about 60% of the PD patients suffer from constipation and other gut related issues from up to 20 years before the diagnosis of Parkinson’s. Hence, alterations in the gut microbiome composition have been studied, reported and their functional consequences have been associated with gut-brain axis and Parkinson’s.